آنتی بادی مونوکلونال فلوسایتومتری CD11c-PE ، کلون B-ly6

Name: Flow Cytometry Antibody CD11c-PE, Clone B-ly6

• Antibody CD11c-PE is a monoclonal antibody (mAb) labelled with R-Phycoerythrin (PE) designed for use as a direct immunofluorescence reagent in the identification and enumeration of cells which express the CD11c antigen by flow cytometry (FC). Anti-CD11c is considered essential for the initial evaluation of B-cell lymphoproliferative disorders together with a panel of other antibodies. This reagent must be used by flow cytometry qualified personal.

SUMMARY AND EXPLANATION

The CYT-11cPE3 MAb reacts with the 150 kDa adhesion glycoprotein (p150, integrin a chain) expressed on NK cells, activated B and T cells, monocytes, neutrophil granulocytes and macrophages. Analysis of the expression of antigen CD11c is useful for the identification and the characterization of hematologic disorders since CD11c is expressed on hairy cell leukemia (HCL) cells, on cells from cases of B-cell chronic lymphocytic leukemia (B-CLL), B-cell prolymphocytic leukemia (B-PLL), splenic marginal zone lymphoma, acute myeloblastic leukemia (AML), acute myelomonocytic leukemia (AMML) and acute megakarioblastic leukemia (AMKL).

REAGENT COMPOSITION

Purified monoclonal CD11c antibody conjugated with R-phycoerythrin (PE), supplied in phosphate buffered saline with 0,09% sodium azide.

• Clone: B-ly6
• Isotype: IgG1
• Purification: Affinity chromatography
• Amount per 1 ml vial: 200 tests (5 ml mAb to 106 cells)
• Reagent is not considered sterile.