آنتی بادی مونوکلونال فلوسایتومتری CD1a-FITC ،کلون NA1-34-HLK

Name: Flow Cytometry Antibody CD1a-FITC, Clone NA1-34-HLK

• Antibody CD1a-FITC is a monoclonal antibody (mAb) labelled with fluorescein isothiocyanate (FITC) designed for flow cytometry use as a direct immunofluorescence reagent in the identification and enumeration of CD1a antigen-expressing cells. This reagent must be used by flow cytometry qualified personal.

SUMMARY AND EXPLANATION

CYT-1AF1 MAb recognizes CD1a antigen, a 49KDa membrane glycoprotein expressed non-covalently with β2- microglobulin. This antigen is found on cortical double positive and single positive thymocytes, Langerhans cells, a subset of dendritic cells and a B cell subset. CD1a has structural similarities to the MHC class I antigen and plays a role in antigen presentation. In addition, CD1a has been implicated in thymic T cell development. It is also present on some T cell leukaemias and lymphomas. Analysis of the expression of the CD1a antigen is useful in the characterization of hematologic neoplasia.

REAGENT COMPOSITION

The purified monoclonal CD1a antibody conjugated with fluorescein isothiocyanate (FITC) is supplied in phosphatebuffered saline (PBS) containing 0.09% sodium azide.

• Clone: NA1/34-HLK.
• Isotype: IgG2a.
• Amount per 1 mL vial: 200 tests (5 µL MAb per determination).
• Reagent is considered non-sterile.